A team of scientists is using tiny, autonomous vehicles or micromotors to test the delivery of drugs to try and clear bacterial infections in the stomach.
University of California, San Diego, Moores Cancer Center Department of Nanoengineering researchers led this new study. They have been conducting trials on mice to tests the utility of their autonomous vehicles.
Micromotors to be Used to Fight Stomach Infections
The micromotors produced by the team are no wider than a human hair and are autonomous. These tiny vehicles were used to clear stomach bacterial infections by delivering the necessary drugs.
The tiny robots were constructed with a magnesium core, which then reacts with the gastric acid after being swallowed. After no more than 20 minutes, the micromotors should release a stream of hydrogen bubbles. These propel the tiny vehicles and send them where they need to go.
The antibiotics released by the vehicles are set to be released as the stomach’s level of acidity diminishes thanks to oxygen. This ensures the medicine’s effectiveness. The micromotors are biodegradable, so they do not require removal or extraction.
For their study, the team tested the Helicobacter pylori bacteria. It then used the clarithromycin as its model antibiotic. The tiny robots were then used over a period of five days in treating the affected mice.
According to results, having them administer the medicine resulted in a noticeable reduction of the stomach bacteria levels. Also, no side-effects or adverse reactions of the stomach function were recorded.
The research team stated that the standard stomach PH level was restored in 24 hours.
Researchers believe that these tiny vehicles show real promise for future treatments. Ones that make use of them in treating bacterial infections and also diseases.
“There is still a long way to go, but we are on a fantastic voyage,” stated Joseph Wang, a professor and nanoengineer.
The team released their study results in a paper in the journal Nature Communications.
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