According to a latest study, the disturbed circadian rhythms along with a diet comprise of high fat and sugar contributes in many harmful conditions specially the inflammatory bowel disease. The study conducted in laboratory on mice.
“Circadian rhythms, which impose a 24-hour cycle on our bodies, are different from sleep patterns, adding that sleep is a consequence of circadian rhythms”, according to Robin M. Voigt, PhD, assistant professor at Rush Medical College and first author of the study.
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Experiment:
A known experience for disruption of inborn circadian rhythms is done on male mice, they had their cycles of exposure to light and dark shifted on a weekly basis. Few mice fed standard food and others high-fat, high-sugar diet
Observation:
Researchers found that the micro biota of the mice with disrupted circadian rhythms were significantly different from that of the control group if they ate high-fat, high-sugar food.
Mice that ate the high-fat, high-sugar diet, and had circadian-rhythm disruptions, had higher concentrations of bacteria that are known to promote inflammation than any of the other mice in the study.
Mice that ate the high-fat, high-sugar diet displayed changes in the makeup of the microorganisms in their guts, regardless of circadian status.
Upsetting the circadian rhythms of the mice fed standard food did not significantly affect the micro biota in their intestines.
Result:
The disturbed circadian rhythms along with a diet comprise of high fat and sugar contributes in inflammatory bowel disease.
While circadian rhythm disturbance may be common among some, the research suggests that it may be contributing to a host of diseases that may be prevented by regulating things such as sleep/wake patterns and times of eating to help prevent circadian rhythm disruption. Including prebiotics or probiotics in the diet can also help normalize the effects of circadian rhythm disruption on the intestinal micro biota to reduce the presence of inflammation.
